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Muscle-specific nucleic acid regulatory elements and methods and use thereof

Thierry VandenDriessche (Uitvinder), Marinee Chuah (Uitvinder), Pieter De Bleser (Uitvinder)

Onderzoeksoutput: Patent

Samenvatting

The present invention relates to nucleic acid regulatory elements that are able to enhance muscle-specific expression of genes, in particular expression in cardiac muscle and/or skeletal muscle, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy, more particularly muscle-directed gene therapy, and for vaccination purposes.
Originele taal-2English
OctrooinummerUS10731177
StatusPublished - 2020

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