Mycophenolate mofetil

D Abramowicz, N Broeders, M Wissing, J Sternon

Onderzoeksoutput: Articlepeer review

1 Citaat (Scopus)

Samenvatting

Mycophenolate Mofetil (MMF) is a new immunosuppressive agent that selectively inhibits the proliferation of T and B lymphocytes. The use of MMF in renal transplantation significantly reduced the incidence of acute rejection episodes in the first year after transplantation. The main toxicities of MMF are the occurrence of diarrhea and leucopenia. This potent immunosuppressive agent is devoid of the nephrotoxicity of cyclosporin and of the multiple adverse effects of corticosteroids. Clinical trials are currently in progress to assess whether the use of MMF will allow the discontinuation of cyclosporine or corticosteroid therapy without leading to an increased risk of rejection. If results were positive, MMF would represent a significant advance in the field of renal transplantation.

Vertaalde titel van de bijdrageMycophenolate mofetil
Originele taal-2French
Pagina's (van-tot)139-143
Aantal pagina's5
TijdschriftRevue Médicale de Bruxelles
Volume19
Nummer van het tijdschrift3
StatusPublished - jun 1998

Keywords

  • Acute Disease
  • Adrenal Cortex Hormones
  • B-Lymphocytes
  • Cell Division
  • Clinical Trials as Topic
  • Cyclosporine
  • Diarrhea
  • Graft Rejection
  • Humans
  • Immunosuppressive Agents
  • Incidence
  • Kidney
  • Kidney Transplantation
  • Leukopenia
  • Mycophenolic Acid
  • Risk Factors
  • T-Lymphocytes

Vingerafdruk

Duik in de onderzoeksthema's van 'Mycophenolate mofetil'. Samen vormen ze een unieke vingerafdruk.

Citeer dit