Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages

Tim Guilliams; Farah El-Turk; Alexander K. Buell; Elizabeth M. O'Day; Francesco A. Aprile; Elin K. Esbjoerner; Michele Vendruscolo; Nunilo Cremades; Els Pardon; Lode Wyns; Mark E. Welland; Jan Steyaert; John Christodoulou; Christopher M. Dobson; Erwin De Genst

doi:10.1016/j.jmb.2013.01.040

Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages

Tim Guilliams, Farah El-Turk, Alexander K. Buell, Elizabeth M. O'Day, Francesco A. Aprile, Elin K. Esbjoerner, Michele Vendruscolo, Nunilo Cremades, Els Pardon, Lode Wyns, Mark E. Welland, Jan Steyaert, John Christodoulou, Christopher M. Dobson, Erwin De Genst

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Originele taal-2	English
Pagina's (van-tot)	2397-2411
Aantal pagina's	15
Tijdschrift	Journal of Molecular Biology
Volume	425
Nummer van het tijdschrift	14
DOI's	https://doi.org/10.1016/j.jmb.2013.01.040
Status	Published - 24 jul 2013

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10.1016/j.jmb.2013.01.040

1-s2.0-S0022283613001897-mainFinal published version, 2,83 MB

SRP13: Structuur en dynamiek van macromoleculaire complexen in gezondheid en ziekte
Steyaert, J., Remaut, H. K., Loris, R., Efremov, R., Steyaert, J., Loris, R. & Remaut, H. K.
1/11/12 → 31/10/24
Project: Fundamenteel

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Guilliams, T., El-Turk, F., Buell, A. K., O'Day, E. M., Aprile, F. A., Esbjoerner, E. K., Vendruscolo, M., Cremades, N., Pardon, E., Wyns, L., Welland, M. E., Steyaert, J., Christodoulou, J., Dobson, C. M., & De Genst, E. (2013). Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages. Journal of Molecular Biology, 425(14), 2397-2411. https://doi.org/10.1016/j.jmb.2013.01.040

Guilliams, Tim ; El-Turk, Farah ; Buell, Alexander K. ; O'Day, Elizabeth M. ; Aprile, Francesco A. ; Esbjoerner, Elin K. ; Vendruscolo, Michele ; Cremades, Nunilo ; Pardon, Els ; Wyns, Lode ; Welland, Mark E. ; Steyaert, Jan ; Christodoulou, John ; Dobson, Christopher M. ; De Genst, Erwin. / Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages. In: Journal of Molecular Biology. 2013 ; Vol. 425, Nr. 14. blz. 2397-2411.

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title = "Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages",

keywords = "synuclein, nanobody, amyloid fibril, NMR, ITC",

author = "Tim Guilliams and Farah El-Turk and Buell, {Alexander K.} and O'Day, {Elizabeth M.} and Aprile, {Francesco A.} and Esbjoerner, {Elin K.} and Michele Vendruscolo and Nunilo Cremades and Els Pardon and Lode Wyns and Welland, {Mark E.} and Jan Steyaert and John Christodoulou and Dobson, {Christopher M.} and {De Genst}, Erwin",

year = "2013",

month = jul,

day = "24",

doi = "10.1016/j.jmb.2013.01.040",

language = "English",

volume = "425",

pages = "2397--2411",

journal = "Journal of Molecular Biology",

issn = "0022-2836",

publisher = "Academic Press Inc.",

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Guilliams, T, El-Turk, F, Buell, AK, O'Day, EM, Aprile, FA, Esbjoerner, EK, Vendruscolo, M, Cremades, N, Pardon, E , Wyns, L, Welland, ME, Steyaert, J, Christodoulou, J, Dobson, CM & De Genst, E 2013, 'Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages', Journal of Molecular Biology, vol. 425, nr. 14, blz. 2397-2411. https://doi.org/10.1016/j.jmb.2013.01.040

Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages. / Guilliams, Tim; El-Turk, Farah; Buell, Alexander K.; O'Day, Elizabeth M.; Aprile, Francesco A.; Esbjoerner, Elin K.; Vendruscolo, Michele; Cremades, Nunilo; Pardon, Els ; Wyns, Lode; Welland, Mark E.; Steyaert, Jan; Christodoulou, John; Dobson, Christopher M.; De Genst, Erwin.

In: Journal of Molecular Biology, Vol. 425, Nr. 14, 24.07.2013, blz. 2397-2411.

Onderzoeksoutput: Article › peer review

TY - JOUR

T1 - Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages

AU - Guilliams, Tim

AU - El-Turk, Farah

AU - Buell, Alexander K.

AU - O'Day, Elizabeth M.

AU - Aprile, Francesco A.

AU - Esbjoerner, Elin K.

AU - Vendruscolo, Michele

AU - Cremades, Nunilo

AU - Pardon, Els

AU - Wyns, Lode

AU - Welland, Mark E.

AU - Steyaert, Jan

AU - Christodoulou, John

AU - Dobson, Christopher M.

AU - De Genst, Erwin

PY - 2013/7/24

Y1 - 2013/7/24

KW - synuclein

KW - nanobody

KW - amyloid fibril

KW - NMR

KW - ITC

U2 - 10.1016/j.jmb.2013.01.040

DO - 10.1016/j.jmb.2013.01.040

M3 - Article

VL - 425

SP - 2397

EP - 2411

JO - Journal of Molecular Biology

JF - Journal of Molecular Biology

SN - 0022-2836

IS - 14

ER -

Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages

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SRP13: Structuur en dynamiek van macromoleculaire complexen in gezondheid en ziekte

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