Nanomotion Detection-Based Rapid Antibiotic Susceptibility Testing

International Joint Research Group VUB-EPFL BioNanotechnology & NanoMedicine (Nano)

Onderzoeksoutput: Article

3 Citaten (Scopus)

Samenvatting

Rapid antibiotic susceptibility testing (AST) could play a major role in fighting multidrug- resistant bacteria. Recently, it was discovered that all living organisms oscillate in the range of nanometers and that these oscillations, referred to as nanomotion, stop as soon the organism dies. This finding led to the development of rapid AST techniques based on the monitoring of these oscillations upon exposure to antibiotics. In this review, we explain the working principle of this novel technique, compare the method with current ASTs, explore its application and give some advice about its implementation. As an illustrative example, we present the application of the technique to the slowly growing and pathogenic Bordetella pertussis bacteria.
Originele taal-2English
Artikelnummer287
Pagina's (van-tot)1-16
Aantal pagina's16
TijdschriftAntibiotics (Basel)
Volume10
Nummer van het tijdschrift3
DOI's
StatusPublished - 10 mrt 2021

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