Background and Aims Our aim is to investigate whether certain baseline NIHSS subitem scores might predict the development of post-stroke delirium (PSD), next to well-known risk factors such as age and baseline stroke severity. Methods In a dataset of 514 patients with acute ischemic stroke, a retrospective chart review was used to diagnose PSD based on DSM-5 criteria. Patients were divided into those who developed delirium within the first week after stroke onset (n = 201) and those who didn’t (n = 313). NIHSS subitem scores on admission were analysed in 488 patients. Multiple logistic regression analysis (MLRA) was used to identify predictors of PSD. Results MLRA, entering all NIHSS subitems after collinearity check, showed that scores ≥ 1 on “level of consciousness” (LOC), “LOC-questions", “LOC -commands", “visual” and “facial palsy” were predictors of PSD. Score ≥ 1 on “ataxia” was associated with a lower risk for PSD. MLRA, entering age > 70 years and baseline NIHSS ≥ 7 next to the NIHSS subitems, showed that age > 70 years (OR 4.61; 95%CI 2.84 –7.50), NIHSS ≥ 7 on admission (OR 2.95; 95% CI = 1.71–5.09), and a score ≥ 1 on “LOC” (OR 2.67; 95%CI = 1.20–5.94), “LOC-commands” (OR 2.06; 95% CI = 1.13–3.73) and “ataxia” (OR 0.11; 95% CI = 0.03–0.53) were independent predictors of PSD. Conclusions "LOC", “LOC-commands” (score ≥1 higher risk) and “ataxia” (score ≥1 lower risk) are the only NIHSS subitems that remain significant predictors of PSD after adjustment for age and stroke severity.
Originele taal-2English
StatusPublished - 3 sep 2021
EvenementEuropean Stroke Organisation Conference 2021 -
Duur: 1 sep 20213 sep 2021


ConferenceEuropean Stroke Organisation Conference 2021


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