Noninvasive imaging of the PD-1:PD-L1 immune checkpoint: Embracing nuclear medicine for the benefit of personalized immunotherapy: Embracing nuclear medicine for the benefit of personalized immunotherapy

Onderzoeksoutput: Scientific review

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Samenvatting

Molecular imaging of the immune checkpoint receptor PD-1 and its ligand PD-L1 is increasingly investigated as a strategy to guide and monitor PD-1:PD-L1-targeted immune checkpoint therapy. We provide an overview of the current state-of-the-art on PD-1- and PD-L1-specific imaging agents for quantitative, real-time assessment of PD-1:PD-L1 expression in the tumor environment and discuss their potential for clinical translation.
Originele taal-2English
Pagina's (van-tot)3559-3570
Aantal pagina's12
TijdschriftTheranostics
Volume8
Nummer van het tijdschrift13
DOI's
StatusPublished - 7 jun 2018

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