Oocyte donation for genetic indications.

Oocyte donation is now a 'routine' treatment for infertility. Oocyte donation is mainly carried out in women with primary ovarian failure or premature menopause or in women in whom different regimens of ovarian stimulation prevent the development of ovarian follicles. In our Centres, oocyte donation is also offered to women or couples who prefer not to use their own gametes because of high recurrent risk of chromosomal or monogenic diseases. The resulting pregnancies in these women as well as in a series of women with gonadal dysgenesis due to X-chromosome aneuploidies are reported.