Samenvatting
The present invention relates to nucleic acid expression cassettes and vectors containing liver- specific regulatory elements and codon-optimized factor IX or factor VIII transgenes, methods employing these expression cassettes and vectors and uses thereof. The present invention is particularly useful for applications using liver-directed gene therapy, in particular for the treatment of hemophilia A and B.
| Originele taal-2 | English |
|---|---|
| Octrooinummer | EP3270944 |
| Status | Published - 2019 |
Vingerafdruk
Duik in de onderzoeksthema's van 'Optimized liver-specific expression systems for fviii and fix'. Samen vormen ze een unieke vingerafdruk.Projecten
- 1 Afgelopen
-
IOF3007: IOF GEAR: RAINboW Verantwoorde AI voor een verbonden wereld
Nowe, A. (Administrative Promotor), Dooms, A. (Co-Promoter), Barbé, K. (Co-Promoter), Verbeke, W. (Co-Promoter), Guns, T. (Co-Promoter), Ginis, V. (Co-Promoter), Loeckx, J. (Mandataris), Schietgat, L. (Mandataris), Radulescu, R.-T. (Mandataris), Loro Velardo, F. (Mandataris), Braeckman, G. (Mandataris), De Canck, H. (Mandataris), Blondeel, M. (Mandataris) & Balcaen, G. (Mandataris)
1/01/19 → 30/06/22
Project: Toegepast
Citeer dit
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver