Peroxiredoxins wear many hats: Factors that fashion their peroxide sensing personalities

Onderzoeksoutput: Article

1 Citaat (Scopus)

Samenvatting

Peroxiredoxins (Prdxs) sense and assess peroxide levels, and signal through protein interactions. Understanding the role of the multiple structural and post-translational modification (PTM) layers that tunes the peroxiredoxin specificities is still a challenge. In this review, we give a tabulated overview on what is known about human and bacterial peroxiredoxins with a focus on structure, PTMs, and protein-protein interactions. Armed with numerous cellular and atomic level experimental techniques, we look at the future and ask ourselves what is still needed to give us a clearer view on the cellular operating power of Prdxs in both stress and non-stress conditions.

Originele taal-2English
Artikelnummer101959
Aantal pagina's17
TijdschriftRedox Biology
Volume42
DOI's
StatusPublished - jun 2021

Vingerafdruk

Duik in de onderzoeksthema's van 'Peroxiredoxins wear many hats: Factors that fashion their peroxide sensing personalities'. Samen vormen ze een unieke vingerafdruk.

Citeer dit