Probiotics in the prevention and management of human diseases: Probiotics in the prevention of allergic diseases (asthma and allergic rhinitis)

Lien Chris Meirlaen, Elvira Ingrid Levy, Yvan Vandenplas

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abstract
Allergic rhinitis and asthma are one of the most frequent allergic diseases. They are increasing in the developing world related to a westernizing lifestyle, while the prevalence is stable to decreasing in the industrialized world. The aim of this paper is to answer the question if prevention and/or treatment of allergic rhinitis and asthma can be achieved by administrating probiotics that might contribute to stabilize the disturbed microbiome that influences the immune system through the gut–lung axis. There is substantial evidence from animal studies in controlled conditions that selected probiotic strains may offer benefit in the prevention of wheezing and asthma, but clinical studies conducted in infants (including as well pre- and postnatal administration) have disappointing outcomes. The latter may be related to the multiple confounding factors, such as environment, strain selection and dosage, moment of administration, and genetic background. Therefore there is insufficient evidence to recommend the administration of probiotics in the prevention and management of allergic rhinitis and asthma.
Originele taal-2English
TitelProbiotics in the prevention and management of human diseases
RedacteurenMitesh Kumar Dwivedi, N Amaresan, A Sankaranarayanan, E. Helen Kemp
UitgeverijElsevier
Hoofdstuk10
Pagina's139-143
Aantal pagina's5
StatusPublished - 2022

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