TY - JOUR
T1 - Procedural Safety and Efficacy for Pulmonary Vein Isolation with the Novel Polarx™ Cryoablation System
T2 - A Propensity Score Matched Comparison with the Arctic Front™ Cryoballoon in the Setting of Paroxysmal Atrial Fibrillation
AU - Mojica, Joerelle
AU - Lipartiti, Felicia
AU - Al Housari, Maysam
AU - Bala, Gezim
AU - Kazawa, Shuichiro
AU - Miraglia, Vincenzo
AU - Monaco, Cinzia
AU - Overeinder, Ingrid
AU - Strazdas, Antanas
AU - Ramak, Robbert
AU - Paparella, Gaetano
AU - Sieira, Juan
AU - Capulzini, Lucio
AU - Sorgente, Antonio
AU - Stroker, Erwin
AU - Brugada, Pedro
AU - De Asmundis, Carlo
AU - Chierchia, Gian-Battista
N1 - Publisher Copyright:
© 2021 CardioFront LLC. All rights reserved.
Copyright:
Copyright 2022 Elsevier B.V., All rights reserved.
PY - 2021/12/25
Y1 - 2021/12/25
N2 - Background: The novel Polarx™ cryoablation system is currently being studied for atrial fibrillation (AF) ablation. To the best of our knowledge, no study comparing the novel cryoablation system with the standard Arctic Front™ cryoballoon is available in today's literature. This study aims to compare Polarx™ and Arctic Front™ cryoballoon in terms of safety and efficacy.Methods: From a total cohort of 202 patients who underwent pulmonary vein (PV) isolation for paroxysmal AF through cryoablation, a population of 30 patients who used Polarx™ were compared with 30 propensity-score matched patients who used Arctic Front™.Results: Pulmonary vein occlusion and electrical isolation were achieved in all (100%) veins with a mean number of 1.09 ± 0.3 occlusion per vein using Polarx™ and 1.19 ± 0.5 occlusion per vein using Arctic Front™ (p = 0.6). Shorter procedure and fluoroscopy time were observed with Polarx™ group (60.5 ± 14.23 vs 73.43 ± 13.26 mins, p = 0.001; 12.83 ± 6.03 vs 17.23 ± 7.17 mins, p = 0.01, respectively). Lower cumulative freeze duration per vein was also observed with Polarx™ (203.38 ± 72.03 vs 224.9 ± 79.35 mins, p = 0.02). There was no significant difference in isolation time between the two groups (34.47 ± 21.23 vs 34.18 ± 26.79 secs, p = 0.9).Conclusions: The novel Polarx™ cryoablation system showed similar efficacy in vein occlusion and isolation and safety profile when compared to Arctic Front™ cryoablation system. Procedure time, fluoroscopy time, and cumulative freeze duration were significantly lower with Polarx™ cryoablation system.
AB - Background: The novel Polarx™ cryoablation system is currently being studied for atrial fibrillation (AF) ablation. To the best of our knowledge, no study comparing the novel cryoablation system with the standard Arctic Front™ cryoballoon is available in today's literature. This study aims to compare Polarx™ and Arctic Front™ cryoballoon in terms of safety and efficacy.Methods: From a total cohort of 202 patients who underwent pulmonary vein (PV) isolation for paroxysmal AF through cryoablation, a population of 30 patients who used Polarx™ were compared with 30 propensity-score matched patients who used Arctic Front™.Results: Pulmonary vein occlusion and electrical isolation were achieved in all (100%) veins with a mean number of 1.09 ± 0.3 occlusion per vein using Polarx™ and 1.19 ± 0.5 occlusion per vein using Arctic Front™ (p = 0.6). Shorter procedure and fluoroscopy time were observed with Polarx™ group (60.5 ± 14.23 vs 73.43 ± 13.26 mins, p = 0.001; 12.83 ± 6.03 vs 17.23 ± 7.17 mins, p = 0.01, respectively). Lower cumulative freeze duration per vein was also observed with Polarx™ (203.38 ± 72.03 vs 224.9 ± 79.35 mins, p = 0.02). There was no significant difference in isolation time between the two groups (34.47 ± 21.23 vs 34.18 ± 26.79 secs, p = 0.9).Conclusions: The novel Polarx™ cryoablation system showed similar efficacy in vein occlusion and isolation and safety profile when compared to Arctic Front™ cryoablation system. Procedure time, fluoroscopy time, and cumulative freeze duration were significantly lower with Polarx™ cryoablation system.
KW - Arctic Front
KW - Atrial fibrillation
KW - Cryoballoon
KW - Polarx
UR - http://www.scopus.com/inward/record.url?scp=85119588570&partnerID=8YFLogxK
U2 - 10.4022/jafib.20200455
DO - 10.4022/jafib.20200455
M3 - Article
C2 - 34950358
VL - 14
JO - Journal of Atrial Fibrillation
JF - Journal of Atrial Fibrillation
SN - 1941-6911
IS - 1
M1 - 20200455
ER -