Promising immunomodulatory effects of selected strains of dairy propionibacteria as evidenced in vitro and in vivo

Benoît Foligné, Stéphanie-Marie Deutsch, Jérôme Breton, Fabien J Cousin, Joëlle Dewulf, Michel Samson, Bruno Pot, Gwénaël Jan

Onderzoeksoutput: Article

70 Citaten (Scopus)

Samenvatting

Immunomodulatory properties of 10 dairy propionibacteria, analyzed on human peripheral blood mononuclear cells (PBMCs), revealed a highly strain-dependent induction of anti-inflammatory cytokine interleukin 10 (IL-10). Two selected strains of Propionibacterium freudenreichii showed a protective effect against two models of colitis in mice, suggesting a probiotic potential predicted by immune-based selection criteria for these cheese starter bacteria.

Originele taal-2English
Pagina's (van-tot)8259-8264
Aantal pagina's6
TijdschriftApplied and Environmental Microbiology
Volume76
Nummer van het tijdschrift24
DOI's
StatusPublished - dec 2010

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