Randall's plaque as the origin of idiopathic calcium oxalate stone formation: an update

Els Van de Perre, Dominique Bazin, Vincent Estrade, Elise Bouderlique, Karl Martin Wissing, Michel Daudon, Emmanuel Letavernier

Onderzoeksoutput: Articlepeer review

3 Citaten (Scopus)
22 Downloads (Pure)


The majority of idiopathic calcium oxalate kidney stones form on the Randall's plaque, a subepithelial calcium phosphate plaque at the renal papilla. The formation mechanisms of the Ran-dall's plaque and associated calcium oxalate stones remain incompletely understood. This article pro-vides an historical overview of the research performed on this topic, describes the current epidemi-ological trends of Randall's plaque-associated kidney stone formation and reviews the suggested for-mation mechanisms of Randall's plaque and associated calcium oxalate stones. Finally, this overview highlights the recent advances made on the subject, including the development of an animal model.
Originele taal-2English
Pagina's (van-tot)373-391
Aantal pagina's18
TijdschriftComptes rendus. Chimie
Nummer van het tijdschriftS1
StatusPublished - 2022

Bibliografische nota

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© 2021 Elsevier Masson SAS. All rights reserved.

Copyright 2021 Elsevier B.V., All rights reserved.


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