TY - JOUR
T1 - Recovery of dialysis patients with COVID-19
T2 - Health outcomes 3 months after diagnosis in ERACODA
AU - ERACODA Collaborators
AU - Hemmelder, Marc H
AU - Noordzij, Marlies
AU - Vart, Priya
AU - Hilbrands, Luuk B
AU - Jager, Kitty J
AU - Abrahams, Alferso C
AU - Arroyo, David
AU - Battaglia, Yuri
AU - Ekart, Robert
AU - Mallamaci, Francesca
AU - Malloney, Sharon-Rose
AU - Oliveira, Joao
AU - Rydzewski, Andrzej
AU - Sridharan, Sivakumar
AU - Vogt, Liffert
AU - Duivenvoorden, Raphaël
AU - Gansevoort, Ron T
AU - Franssen, Casper F M
AU - Wissing, Karl Martin
N1 - © The Author(s) 2022. Published by Oxford University Press on behalf of the ERA.
PY - 2022/5/25
Y1 - 2022/5/25
N2 - BACKGROUND: COVID-19-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients three months after their COVID-19 diagnosis.METHODS: We analyzed data on dialysis patients diagnosed with COVID-19 from February 1st, 2020-March 31st, 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residency, and functional- and mental health status (estimated by their treating physician) three months after COVID-19 diagnosis. Complete follow-up data was available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression.RESULTS: In 2449 hemodialysis patients (mean ± SD age: 67.5 ± 14.4 years, 62% male) survival probabilities at three months after COVID-19 diagnosis were 90% for non-hospitalized patients (N = 1087), 73% for patients admitted to the hospital but not to an ICU (N = 1165) and 40% for those admitted to an ICU (N = 197). Patient survival hardly decreased between 28 days and three months after COVID-19 diagnosis. At three months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (between 0.8 and 6.3%) or a nursing home (approximately 5%). Higher age and frailty score at presentation and ICU admission were associated with worse functional outcome.CONCLUSIONS: Mortality between 28 days and 3 months after COVID-19 diagnosis was low, and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at three months after diagnosis.
AB - BACKGROUND: COVID-19-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients three months after their COVID-19 diagnosis.METHODS: We analyzed data on dialysis patients diagnosed with COVID-19 from February 1st, 2020-March 31st, 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residency, and functional- and mental health status (estimated by their treating physician) three months after COVID-19 diagnosis. Complete follow-up data was available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression.RESULTS: In 2449 hemodialysis patients (mean ± SD age: 67.5 ± 14.4 years, 62% male) survival probabilities at three months after COVID-19 diagnosis were 90% for non-hospitalized patients (N = 1087), 73% for patients admitted to the hospital but not to an ICU (N = 1165) and 40% for those admitted to an ICU (N = 197). Patient survival hardly decreased between 28 days and three months after COVID-19 diagnosis. At three months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (between 0.8 and 6.3%) or a nursing home (approximately 5%). Higher age and frailty score at presentation and ICU admission were associated with worse functional outcome.CONCLUSIONS: Mortality between 28 days and 3 months after COVID-19 diagnosis was low, and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at three months after diagnosis.
KW - COVID-19
KW - dialysis
KW - functional health status
KW - mental health status
KW - survival
UR - http://www.scopus.com/inward/record.url?scp=85129660616&partnerID=8YFLogxK
U2 - 10.1093/ndt/gfac008
DO - 10.1093/ndt/gfac008
M3 - Article
C2 - 35030246
VL - 37
SP - 1140
EP - 1151
JO - Nephrology Dialysis Transplantation
JF - Nephrology Dialysis Transplantation
SN - 0931-0509
IS - 6
ER -