RNA transcription vector and uses thereof

Carlo Heirman; Kris Thielemans

RNA transcription vector and uses thereof

Carlo Heirman (Uitvinder)
, Kris Thielemans (Uitvinder)

Onderzoeksoutput: Patent

Samenvatting

The present invention relates to an improved RNA transcription vector, which is very suitable for the production of mRNA for in vivo therapeutic purposes. The improvements in the vector reside in the presence of a translation enhancer (TE) and a nuclear retention element (NRS), especially when the latter is the “Expression and Nuclear Retention Element” (ENE) of Kaposi's sarcoma associated Herpes virus (KSHV).

Originele taal-2	English
Octrooinummer	US10159755
Status	Published - 2018

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https://worldwide.espacenet.com/patent/search/family/049578161/publication/US10159755B2?q=US10159755

IOF242: Financiering IOF-programma vakgroep ETRO (1 en 2)
Stiens, J. (Administrative Promotor), Thielemans, S. (Mandataris), Ersu, B. (Mandataris) & Pourkazemi, A. (Mandataris)
1/01/16 → 31/12/20
Project: Toegepast

Citeer dit

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title = "RNA transcription vector and uses thereof",

abstract = "The present invention relates to an improved RNA transcription vector, which is very suitable for the production of mRNA for in vivo therapeutic purposes. The improvements in the vector reside in the presence of a translation enhancer (TE) and a nuclear retention element (NRS), especially when the latter is the “Expression and Nuclear Retention Element” (ENE) of Kaposi's sarcoma associated Herpes virus (KSHV). ",

author = "Carlo Heirman and Kris Thielemans",

year = "2018",

language = "English",

type = "Patent",

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TY - PAT

T1 - RNA transcription vector and uses thereof

AU - Heirman, Carlo

AU - Thielemans, Kris

PY - 2018

Y1 - 2018

N2 - The present invention relates to an improved RNA transcription vector, which is very suitable for the production of mRNA for in vivo therapeutic purposes. The improvements in the vector reside in the presence of a translation enhancer (TE) and a nuclear retention element (NRS), especially when the latter is the “Expression and Nuclear Retention Element” (ENE) of Kaposi's sarcoma associated Herpes virus (KSHV).

AB - The present invention relates to an improved RNA transcription vector, which is very suitable for the production of mRNA for in vivo therapeutic purposes. The improvements in the vector reside in the presence of a translation enhancer (TE) and a nuclear retention element (NRS), especially when the latter is the “Expression and Nuclear Retention Element” (ENE) of Kaposi's sarcoma associated Herpes virus (KSHV).

UR - https://worldwide.espacenet.com/patent/search/family/049578161/publication/US10159755B2?q=US10159755

M3 - Patent

M1 - US10159755

ER -

RNA transcription vector and uses thereof

Samenvatting

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Projecten

IOF242: Financiering IOF-programma vakgroep ETRO (1 en 2)

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