Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli 0104: H4 strain from the 2011 outbrak in Germany

Maia Meribishvili; D. De Vos; Gilbert Verbeken; Andrew Kropinski; D. Vandenheuvel; R. Lavigne; P. Wattiau; J. Mast; Catherine Ragimbeau; Joel Mossong; Jacques Scheres; N. Chanishvili; M Vaneechoutte; Jean-Paul Pirnay; Queen Astrid Mil Hosp; Lab Mol; Cellular Technol; [No Value] Brussels; [No Value] Belgium

Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli 0104: H4 strain from the 2011 outbrak in Germany

Maia Meribishvili, D. De Vos, Gilbert Verbeken, Andrew Kropinski, D. Vandenheuvel, R. Lavigne, P. Wattiau, J. Mast, Catherine Ragimbeau, Joel Mossong, Jacques Scheres, N. Chanishvili, M Vaneechoutte, Jean-Paul Pirnay, Queen Astrid Mil Hosp (Redacteur), Lab Mol (Redacteur), Cellular Technol (Redacteur), [No Value] Brussels (Redacteur), [No Value] Belgium (Redacteur)

Onderzoeksoutput: Article › peer review

Samenvatting

In 2011, a novel strain of O104:H4 Escherichia coli caused a serious outbreak of foodborne hemolytic uremic syndrome and bloody diarrhea in Germany. Antibiotics were of questionable use and 54 deaths occurred. Candidate therapeutic bacteriophages that efficiently lyse the E. coli O104:H4 outbreak strain could be selected rather easily from a phage bank or isolated from the environment. It is argued that phage therapy should be more considered as a potential armament against the growing threat of (resistant) bacterial infections.

Originele taal-2	English
Tijdschrift	PLoS ONE
Volume	12
Nummer van het tijdschrift	7
Status	Published - dec 1970

Bibliografische nota

Queen Astrid Mil Hosp, Lab Mol & Cellular Technol, Brussels, Belgium.

Citeer dit

Meribishvili, M., De Vos, D., Verbeken, G., Kropinski, A., Vandenheuvel, D., Lavigne, R., Wattiau, P., Mast, J., Ragimbeau, C., Mossong, J., Scheres, J., Chanishvili, N., Vaneechoutte, M., Pirnay, J-P., Hosp, Q. A. M. (editor), Mol, L. (editor), Technol, C. (editor), Brussels, N. V. (editor), & Belgium, N. V. (editor) (1970). Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli 0104: H4 strain from the 2011 outbrak in Germany. PLoS ONE, 12(7).

Meribishvili, Maia ; De Vos, D. ; Verbeken, Gilbert ; Kropinski, Andrew ; Vandenheuvel, D. ; Lavigne, R. ; Wattiau, P. ; Mast, J. ; Ragimbeau, Catherine ; Mossong, Joel ; Scheres, Jacques ; Chanishvili, N. ; Vaneechoutte, M ; Pirnay, Jean-Paul ; Hosp, Queen Astrid Mil (Redacteur) ; Mol, Lab (Redacteur) ; Technol, Cellular (Redacteur) ; Brussels, [No Value] (Redacteur) ; Belgium, [No Value] (Redacteur). / Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli 0104: H4 strain from the 2011 outbrak in Germany. In: PLoS ONE. 1970 ; Vol. 12, Nr. 7.

@article{17c13d9baf7b4b9f8732f1e31f62df21,

title = "Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli 0104: H4 strain from the 2011 outbrak in Germany",

abstract = "In 2011, a novel strain of O104:H4 Escherichia coli caused a serious outbreak of foodborne hemolytic uremic syndrome and bloody diarrhea in Germany. Antibiotics were of questionable use and 54 deaths occurred. Candidate therapeutic bacteriophages that efficiently lyse the E. coli O104:H4 outbreak strain could be selected rather easily from a phage bank or isolated from the environment. It is argued that phage therapy should be more considered as a potential armament against the growing threat of (resistant) bacterial infections.",

keywords = "Phage therapy",

author = "Maia Meribishvili and {De Vos}, D. and Gilbert Verbeken and Andrew Kropinski and D. Vandenheuvel and R. Lavigne and P. Wattiau and J. Mast and Catherine Ragimbeau and Joel Mossong and Jacques Scheres and N. Chanishvili and M Vaneechoutte and Jean-Paul Pirnay and Hosp, {Queen Astrid Mil} and Lab Mol and Cellular Technol and Brussels, {[No Value]} and Belgium, {[No Value]}",

note = "Queen Astrid Mil Hosp, Lab Mol & Cellular Technol, Brussels, Belgium.",

year = "1970",

month = dec,

language = "English",

volume = "12",

journal = "PLoS ONE",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "7",

}

Meribishvili, M, De Vos, D, Verbeken, G, Kropinski, A, Vandenheuvel, D, Lavigne, R, Wattiau, P, Mast, J, Ragimbeau, C, Mossong, J, Scheres, J, Chanishvili, N, Vaneechoutte, M, Pirnay, J-P, Hosp, QAM (redactie), Mol, L (redactie), Technol, C (redactie), Brussels, NV (redactie) & Belgium, NV (redactie) 1970, 'Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli 0104: H4 strain from the 2011 outbrak in Germany', PLoS ONE, vol. 12, nr. 7.

Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli 0104: H4 strain from the 2011 outbrak in Germany. / Meribishvili, Maia; De Vos, D.; Verbeken, Gilbert; Kropinski, Andrew; Vandenheuvel, D.; Lavigne, R.; Wattiau, P.; Mast, J.; Ragimbeau, Catherine; Mossong, Joel; Scheres, Jacques; Chanishvili, N.; Vaneechoutte, M; Pirnay, Jean-Paul; Hosp, Queen Astrid Mil (Redacteur); Mol, Lab (Redacteur); Technol, Cellular (Redacteur); Brussels, [No Value] (Redacteur); Belgium, [No Value] (Redacteur).

In: PLoS ONE, Vol. 12, Nr. 7, 12.1970.

Onderzoeksoutput: Article › peer review

TY - JOUR

T1 - Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli 0104: H4 strain from the 2011 outbrak in Germany

AU - Meribishvili, Maia

AU - De Vos, D.

AU - Verbeken, Gilbert

AU - Kropinski, Andrew

AU - Vandenheuvel, D.

AU - Lavigne, R.

AU - Wattiau, P.

AU - Mast, J.

AU - Ragimbeau, Catherine

AU - Mossong, Joel

AU - Scheres, Jacques

AU - Chanishvili, N.

AU - Vaneechoutte, M

AU - Pirnay, Jean-Paul

A2 - Hosp, Queen Astrid Mil

A2 - Mol, Lab

A2 - Technol, Cellular

A2 - Brussels, [No Value]

A2 - Belgium, [No Value]

N1 - Queen Astrid Mil Hosp, Lab Mol & Cellular Technol, Brussels, Belgium.

PY - 1970/12

Y1 - 1970/12

N2 - In 2011, a novel strain of O104:H4 Escherichia coli caused a serious outbreak of foodborne hemolytic uremic syndrome and bloody diarrhea in Germany. Antibiotics were of questionable use and 54 deaths occurred. Candidate therapeutic bacteriophages that efficiently lyse the E. coli O104:H4 outbreak strain could be selected rather easily from a phage bank or isolated from the environment. It is argued that phage therapy should be more considered as a potential armament against the growing threat of (resistant) bacterial infections.

AB - In 2011, a novel strain of O104:H4 Escherichia coli caused a serious outbreak of foodborne hemolytic uremic syndrome and bloody diarrhea in Germany. Antibiotics were of questionable use and 54 deaths occurred. Candidate therapeutic bacteriophages that efficiently lyse the E. coli O104:H4 outbreak strain could be selected rather easily from a phage bank or isolated from the environment. It is argued that phage therapy should be more considered as a potential armament against the growing threat of (resistant) bacterial infections.

KW - Phage therapy

M3 - Article

VL - 12

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 7

ER -

Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli 0104: H4 strain from the 2011 outbrak in Germany

Samenvatting

Bibliografische nota

Vingerafdruk

Citeer dit