Size of cortical bone and relationship to bone mineral density assessed by quantitative computed tomography image segmentation

O Louis, P Van den Winkel, P Covens, A Schoutens, M Osteaux

Onderzoeksoutput: Articlepeer review

24 Citaten (Scopus)

Samenvatting

RATIONALE AND OBJECTIVES: The accuracy of the measurement of the size of cortical bone on computed tomography (CT) images of human vertebrae was evaluated using an automated contour detection and segmentation procedure.

METHODS: Forty human lumbar vertebrae were scanned using 8-mm slices and an automated detection for definition of trabecular and cortical region of interest. The vertebrae were embedded in a polyester resin and 8-mm-thick midvertebral specimens were excised using a diamond circular saw. Contact radiographs of these specimens were performed and, after photograph magnification, the cortical area was measured using computerized planimetry.

RESULTS: Cortical area measured on CT images was highly correlated with the area measured by planimetry on the specimens (r = .91; P < .001) with, however, a systematic over-estimation. A significant relationship was found between density and width of the cortex (r = .56; P < .001).

CONCLUSIONS: Computed tomography is able to assess the size of cortical bone in human vertebrae, but a threshold detection algorithm, as used in the current study, is not adequate to obtain the precise anatomic dimensions.

Originele taal-2English
Pagina's (van-tot)802-805
Aantal pagina's4
TijdschriftInvestigative Radiology
Volume28
Nummer van het tijdschrift9
StatusPublished - sep 1993

Keywords

  • Aged
  • Aged, 80 and over
  • Bone Density
  • Bone and Bones
  • Female
  • Humans
  • Male
  • Tomography, X-Ray Computed

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