Samenvatting

The unprecedented COVID-19 pandemic took the form of successive variant waves, spreading across the globe. We wanted to investigate any shift in hospitalised patients’ profiles throughout the pandemic. For this study, we used a registry that collected data automatically from electronic patient health records. We compared clinical data and severity scores, using the National Institute of Health (NIH) severity scores, from all patients admitted for COVID-19 during four SARS-CoV-2 variant waves. Our study concluded that patients hospitalised for COVID-19 showed very different profiles across the four variant waves in Belgium. Patients were younger during the Alpha and Delta waves and frailer during the Omicron period. ‘Critical’ patients according to the NIH criteria formed the largest fraction among the Alpha wave patients (47.7%), while ‘severe’ patients formed the largest fraction among Omicron patients (61.6%). We discussed host factors, vaccination status, and other confounders to put this into perspective. High-quality real-life data remain crucial to inform stakeholders and policymakers that shifts in patients’ clinical profiles have an impact on clinical practice.
Originele taal-2English
Artikelnummer618
Aantal pagina's11
TijdschriftViruses
Volume15
Nummer van het tijdschrift3
DOI's
StatusPublished - 23 feb 2023

Bibliografische nota

Publisher Copyright:
© 2023 by the authors.

Copyright:
Copyright 2023 Elsevier B.V., All rights reserved.

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