Synthesis of Piperidinone and Azepanone Fused Indoles via a Wagner-Meerwein Type 1,2-Amide Migration of 2-Spiropseudo-indoxyls

Niels Marien, Ting Luo, Guido Verniest

Onderzoeksoutput: Article

4 Citaten (Scopus)

Samenvatting

Spiropseudoindoxyls were synthesized by using a gold(III)-catalyzed intramolecular nitroalkyne redox-dipolar cycloaddition cascade. These compounds were then transformed into novel piperidinone and azepanone fused indoles via a straightforward hydrogenation. The reaction mechanism of this ring expansion is believed to proceed through a rare Wagner-Meerwein type 1,2-amide migration.

Originele taal-2English
Artikelnummerst-2016-b0779-l
Pagina's (van-tot)934-938
Aantal pagina's5
TijdschriftSynlett
Volume28
Nummer van het tijdschrift8
DOI's
StatusPublished - 12 mei 2017

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