Temperature-guided ablation with the second-generation cryoballoon for paroxysmal atrial fibrillation: 3-year follow-up in a multicenter experience

Gaetano Paparella, Saverio Iacopino, Thiago Guimarães Osório, Juan Pablo Abugattas de Torres, Erwin Ströker, Juan Sieira, Hannes Vanacker, Bernard De Ruyter, Serge Boveda, Riccardo Maj, Gianluca Borio, Alessandro Rizzo, Alessio Galli, Pedro Brugada, Carlo de Asmundis, Gian-Battista Chierchia

Onderzoeksoutput: Article

1 Citaat (Scopus)

Samenvatting

PURPOSE: A strategy based on the attainment of the specific parameter of - 40 °C within the first 60 s during cryoenergy applications in the setting of cryoballoon ablation (CB-A) without the use of an inner lumen mapping catheter (ILMC) (Achieve; Medtronic, USA) for the visualization of real-time recordings (RTR) has been previously described. The latter has proven to be very effective in guaranteeing freedom from atrial arrhythmias in patients affected by paroxysmal atrial fibrillation (PAF) at 1-year follow-up. The purpose of this retrospective observational study was to evaluate the clinical outcomes of this strategy in a multicenter experience on a long-term follow-up of 3 years.

METHODS: A total of 192 patients having undergone CB ablation for paroxysmal AF (PAF) starting from September 2015 to November 2016 that underwent a temperature-guided approach were included.

RESULTS: Mean procedural time was 68.77 ± 18.88. The mean number of freezes in the LSPV was 1.2 ± 0.4, 1.2 ± 0.4 in the LIPV, 1.1 ± 0.4 in the RSPV, and 1.2 ± 0.4 in the RIPV. Considering a blanking period of 3 months, freedom from AF off-AAD was achieved in 77.6% (149/192) at mean 34.5 ± 5.5 months and median 35.1 months (IQR, 32.3-37.0 months) follow-up after 1 procedure.

CONCLUSIONS: A temperature-guided approach affords freedom from AF at a 3-year follow-up period in a large majority of patients affected by PAF having undergone a single CB-A procedure.

Originele taal-2English
Pagina's (van-tot)95-104
Aantal pagina's10
TijdschriftJournal of Interventional Cardiac Electrophysiology : An International Journal of Arrhythmias and Pacing
Volume61
Nummer van het tijdschrift1
Vroegere onlinedatum2020
DOI's
StatusPublished - jun 2021

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