The Impact of Elevated Progesterone on the Initiation of an Artificially Prepared Frozen Embryo Transfer Cycle: A Case Series

Panagiotis Drakopoulos; Corina Mat; Nikolaos P Polyzos; Samuel Santos-Ribeiro; Arne van de Vijver; Liesbet Van Landuyt; Herman Tournaye; Christophe Blockeel

doi:10.2174/1389201018666170808125834

The Impact of Elevated Progesterone on the Initiation of an Artificially Prepared Frozen Embryo Transfer Cycle: A Case Series

Panagiotis Drakopoulos, Corina Mat, Nikolaos P Polyzos, Samuel Santos-Ribeiro, Arne van de Vijver, Liesbet Van Landuyt, Herman Tournaye, Christophe Blockeel

Onderzoeksoutput: Article › peer review

3 Citaten (Scopus)

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BACKGROUND: The role of elevated baseline progesterone (P) levels in outcomes of frozen embryo transfers (FET) performed in an artificial cycle has not been investigated yet.

OBJECTIVE: To evaluate the role of elevated P in artificial FET.

METHOD: Case series study of 12 patients with high P levels undergoing artificial FET recruited during a 6-month period in a tertiary referral center.

RESULTS: The clinical pregnancy rate per transfer was 4/12 (33.3%). The biochemical pregnancy rate was 6/12 (50.0%).

CONCLUSION: Elevated levels of P do not seem to have a negative impact on reproductive outcome, and may even be associated with high clinical and biochemical pregnancy rates. Further prospective or large retrospective studies are required to examine the clinical importance of our findings in a larger population.

Originele taal-2	English
Pagina's (van-tot)	619-621
Aantal pagina's	3
Tijdschrift	Current Pharmaceutical Biotechnology
Volume	18
Nummer van het tijdschrift	8
DOI's	https://doi.org/10.2174/1389201018666170808125834
Status	Published - 10 nov. 2017

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abstract = "BACKGROUND: The role of elevated baseline progesterone (P) levels in outcomes of frozen embryo transfers (FET) performed in an artificial cycle has not been investigated yet.OBJECTIVE: To evaluate the role of elevated P in artificial FET.METHOD: Case series study of 12 patients with high P levels undergoing artificial FET recruited during a 6-month period in a tertiary referral center.RESULTS: The clinical pregnancy rate per transfer was 4/12 (33.3%). The biochemical pregnancy rate was 6/12 (50.0%).CONCLUSION: Elevated levels of P do not seem to have a negative impact on reproductive outcome, and may even be associated with high clinical and biochemical pregnancy rates. Further prospective or large retrospective studies are required to examine the clinical importance of our findings in a larger population.",

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author = "Panagiotis Drakopoulos and Corina Mat and Polyzos, {Nikolaos P} and Samuel Santos-Ribeiro and {van de Vijver}, Arne and {Van Landuyt}, Liesbet and Herman Tournaye and Christophe Blockeel",

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doi = "10.2174/1389201018666170808125834",

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AU - Drakopoulos, Panagiotis

AU - Mat, Corina

AU - Polyzos, Nikolaos P

AU - Santos-Ribeiro, Samuel

AU - van de Vijver, Arne

AU - Van Landuyt, Liesbet

AU - Tournaye, Herman

AU - Blockeel, Christophe

PY - 2017/11/10

Y1 - 2017/11/10

N2 - BACKGROUND: The role of elevated baseline progesterone (P) levels in outcomes of frozen embryo transfers (FET) performed in an artificial cycle has not been investigated yet.OBJECTIVE: To evaluate the role of elevated P in artificial FET.METHOD: Case series study of 12 patients with high P levels undergoing artificial FET recruited during a 6-month period in a tertiary referral center.RESULTS: The clinical pregnancy rate per transfer was 4/12 (33.3%). The biochemical pregnancy rate was 6/12 (50.0%).CONCLUSION: Elevated levels of P do not seem to have a negative impact on reproductive outcome, and may even be associated with high clinical and biochemical pregnancy rates. Further prospective or large retrospective studies are required to examine the clinical importance of our findings in a larger population.

AB - BACKGROUND: The role of elevated baseline progesterone (P) levels in outcomes of frozen embryo transfers (FET) performed in an artificial cycle has not been investigated yet.OBJECTIVE: To evaluate the role of elevated P in artificial FET.METHOD: Case series study of 12 patients with high P levels undergoing artificial FET recruited during a 6-month period in a tertiary referral center.RESULTS: The clinical pregnancy rate per transfer was 4/12 (33.3%). The biochemical pregnancy rate was 6/12 (50.0%).CONCLUSION: Elevated levels of P do not seem to have a negative impact on reproductive outcome, and may even be associated with high clinical and biochemical pregnancy rates. Further prospective or large retrospective studies are required to examine the clinical importance of our findings in a larger population.

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DO - 10.2174/1389201018666170808125834

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The Impact of Elevated Progesterone on the Initiation of an Artificially Prepared Frozen Embryo Transfer Cycle: A Case Series

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