Two-year follow-up of one-stage left unilateral thoracoscopic epicardial and transcatheter endocardial ablation for persistent and long-standing persistent atrial fibrillation

Carlo de Asmundis, Varnavas Varnavas, Juan Sieira, Erwin Ströker, Henrique E Coutiño, Muryo Terasawa, Juan Pablo Abugattas, Francesca Salghetti, Riccardo Maj, Osório Thiago Guimarães, Saverio Iacopino, Vincent Umbrain, Jan Poelaert, Pedro Brugada, Sandro Gelsomino, Gian-Battista Chierchia, Mark La Meir

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1 Citaat (Scopus)

Samenvatting

PURPOSE: The purpose of this study was to analyze the efficacy and complication rates of a one-stage left unilateral thoracoscopic hybrid procedure in a series of patients with persistent and long-standing persistent atrial fibrillation (AF) in a 2-year follow-up.

METHODS: Fifty-one consecutive patients (34 males, 65.7 ± 8 years) having undergone hybrid isolation of pulmonary veins (PVs) and posterior wall of left atrium (LA) by means of left unilateral hybrid thoracoscopic ablation for symptomatic persistent (n = 22, 43%) and long-standing persistent atrial fibrillation (AF) (n = 29, 57%) were analyzed.

RESULTS: At a mean follow-up of 24.9 ± 11.8 months (median 24), the success rate without antiarrhythmic therapy was achieved in 68.6% of patients. Procedure-related major complications were observed in 2 patients (4%) including diaphragmatic perforation and late pericardial tamponade requiring mini left-sided thoracotomy and pericardial drainage, respectively. The success rate did not significantly differ between persistent and long-standing persistent AF (respectively, 68.2 and 69%; P = 0.89). Patients with AF relapse during the blanking period were 3.8 times more likely to have AF recurrence after 3 months from the ablation procedure.

CONCLUSION: The hybrid one-stage left unilateral thoracoscopic procedure exhibits encouraging results in the setting of both persistent and long-standing persistent AF after a 2-year follow-up, at a low rate of adverse events.

Originele taal-2English
Pagina's (van-tot)333-343
Aantal pagina's11
TijdschriftJournal of Interventional Cardiac Electrophysiology
Volume58
Nummer van het tijdschrift3
Vroegere onlinedatum13 sep 2019
DOI's
StatusPublished - sep 2020

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